neuroticthought:

skunkbear:

As Virginia Hughes noted in a recent piece for National Geographic’s Phenomena blog, the most common depiction of a synapse (that communicating junction between two neurons) is pretty simple:

Signal molecules leave one neuron from that bulby thing, float across a gap, and are picked up by receptors on the other neuron. In this way, information is transmitted from cell to cell … and thinking is possible.

But thanks to a bunch of German scientists - we now have a much more complete and accurate picture. They’ve created the first scientifically accurate 3D model of a synaptic bouton (that bulby bit) complete with every protein and cytoskeletal element.

This effort has been made possible only by a collaboration of specialists in electron microscopy, super-resolution light microscopy (STED), mass spectrometry, and quantitative biochemistry.

says the press release. The model reveals a whole world of neuroscience waiting to be explored. Exciting stuff!

You can access the full video of their 3D model here.

Credit: Benjamin G. Wilhelm, Sunit Mandad, Sven Truckenbrodt, Katharina Kröhnert, Christina Schäfer, Burkhard Rammner, Seong Joo Koo, Gala A. Claßen, Michael Krauss, Volker Haucke, Henning Urlaub, Silvio O. Rizzoli

In case you all missed it.

ethiopienne:

Help fund Happy Birthday, Marsha!

Happy Birthday, Marsha! tells the story of legendary best friends, Marsha “Pay it No Mind” Johnson and Sylvia Rivera, and the bold everyday decisions they made that helped spark the 1969 Stonewall riots. 

When Marsha and Sylvia, self-proclaimed “street queens” – homeless, Black & Latina trans women – ignite the Stonewall Rebellion, they change LGBT politics forever. It’s a hot summer day in June, 1969. Marsha throws a party, but no one shows up. Meanwhile, Sylvia gets stoned and forgets the party after unsuccessfully introducing her lover to her family. Throughout the difficult day, the friends struggle with harassment and alienation before converging at the Stonewall Inn to finally celebrate Marsha’s birth. Unbeknownst to them, the NYPD has plans to raid the bar that night. Happy Birthday, Marsha! is the story of two brave best friends and the everyday decisions they made that changed the course of history.

Why are we making Happy Birthday, Marsha?
We truly believe how we tell the stories of our heroes matters, so we are drawing upon our community to make this film because we have an opportunity to make a movie written, directed and produced by people living Sylvia & Marsha’s legacy through our own work. It’s been 45 years since the Stonewall rebellion yet the leading role that street queens, trans women of color and gender non-conforming people had during the riots hasn’t received the recognition it deserves. By making Happy Birthday, Marsha! we are seeking to change that, but we need your help to make it happen.

zankie-cookies:

you:

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me:

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Lake day with @chris.frills

“You may think I’m small, but I have a universe in my head.”

— Yoko Ono (via purplebuddhaproject)

Slowly replacing the negative thoughts with colors and beautiful things.

(Source: mywhisperedcolors)

Painted an accent wall in my new bedroom!!!

“The poison leaves bit by bit, not all at once. Be patient. You are healing.”

Yasmin Mogahed (via beautifulsabr)